|CCL 06.03.26 Frontiers in Chemical Biology: Single Molecules, Cambridge , United Kingdom|
From: chemistry-request at ccl.net
To: chemistry-request at ccl.net
Date: Sat Oct 22 17:59:19 2005
Subject: 06.03.26 Frontiers in Chemical Biology: Single Molecules, Cambridge , United Kingdom
Frontiers in Chemical Biology: Single Molecules University of Cambridge , Cambridge , United Kingdom 26 March 2006 - 29 March 2006 http://www.rsc.org/ConferencesAndEvents/RSCConferences/SingleMolecules/ Introduction Run by the RSCs Chemical Biology Forum, this three-day meeting will feature all types of single-molecule experiment, and will include both techniques innovation and the application to important problems in biology. Single-molecule experiments of various kinds are having a revolutionary effect in many of areas of biology. These include new ways to localise and observe functioning molecular complexes, and spectroscopic observations giving distance information on single molecules. These experiments can reveal structural transitions that cannot be synchronised, and are therefore very difficult to study by ensemble methods. Intermediates can be observed, and temporally correlated. A new area of single-molecule enzymology is emerging using these approaches. Other kinds of single-molecule experiments involve the application of forces to individual molecules, including stretching (optical traps, AFM, flow) and twisting (magnetic traps). Proteins and nucleic acids can be pulled apart in a carefully controlled manner giving the order and energetics of these processes. Torsional forces can be mechanically introduced into single DNA molecules, and the action of single enzymes on these substrates studied. Topics Molecular Motors Fluorescence spectroscopy Stretching force Single-molecule enzymology Optical traps Nucleic acids and proteins Twisting/magnetic traps Scanning probe techniques Structural transitions Order and energetics Applications of single-molecule techniques Organising Committee David Lilley University of Dundee, UK Shankar Balasubramanian University of Cambridge, UK Taekjip Ha University of Illinois, Urbana-Champaign, USA Co-Sponsor The Institute of Physics are co-sponsors of 'Frontiers in Chemical Biology: Single Molecules'. IOP members are entitled to register at RSC Member rate to attend the conference. Sponsors We are grateful for the sponsorship support of the following organisations towards the running of the conference: Cancer Research UK BBSRC ISS, Inc. Solexa LtdNOTE THAT E-MAIL ADDRESSES HAVE BEEN MODIFIED!!!
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