From owner-chemistry@ccl.net Mon Feb 6 08:16:00 2012 From: "Massimiliano Porrini M.Porrini#,#ed.ac.uk" To: CCL Subject: CCL: Proline backbone nitrogen pKa/pKb Message-Id: <-46248-120206074842-11754-zWXnxciit+WExMXENSovUw/a\server.ccl.net> X-Original-From: Massimiliano Porrini Content-Transfer-Encoding: 8bit Content-Type: text/plain; charset=ISO-8859-1 Date: Mon, 6 Feb 2012 12:48:29 +0000 MIME-Version: 1.0 Sent to CCL by: Massimiliano Porrini [M.Porrini[a]ed.ac.uk] Hi all, I hope my following question is not that far from the scope of this mailing list. Does anybody know any reference where I could get the value of the pK_a (or related pK_b) of the backbone nitrogen of proline residue as a part of a peptide/protein (not the lone proline) ? Any hint would be really appreciated. Best, -- Dr Massimiliano Porrini Institute for Condensed Matter and Complex Systems School of Physics & Astronomy The University of Edinburgh James Clerk Maxwell Building The King's Buildings Mayfield Road Edinburgh EH9 3JZ Tel +44-(0)131-650-5229 E-mails : M.Porrini~!~ed.ac.uk              mozz76~!~gmail.com              maxp~!~iesl.forth.gr