Announce: Amber 5.0 is available



 It gives us great pleasure to announce the release of AMBER 5.0.  This code
 is a joint effort of the Kollman group at UCSF, the Case group at The
 Scripps Research Institute, David Pearlman at Vertex, the Merz group at
 Pennsylvania State University, Tom Darden at NIEHS, and David Ferguson
 at the University of Minnesota.
 As in the past, this version of AMBER will be jointly supported by Oxford
 Molecular (OM) as well as by the various authors.  Oxford Molecular will
 offer commercial-level support and update services and the option of
 bundling AMBER with their other complementary software.
 AMBER 5.0 (1997) represents a significant change from the most recent
 previous version, 4.1, which was released in 1995.  Briefly, the major
 differences include:
 (1) an updated and parallelized implementation of the particle-mesh Ewald
 routine, and its incorporation into the free energy module;
 (2) "locally-enhanced sampling" (LES) code that allows parts of the
 system
 to be present as multiple copies;
 (3) an alternate version of Sander (ROAR) that includes the ability to
 define part of the system as a quantum-mechanical section (QM/MM), and
 includes alternate integrators;
 (4) PROFEC (pictorial representation of free energy changes), a set of tools
 for carrying out and displaying extrapolative free energy changes;
 (5) new and parallelized methods for NMR refinement; incorporation of penalites
 based on pseudocontact shifts.
 (6) updates to the functionality and stability of LEaP.
 If you are interested in obtaining a copy of AMBER 5.0, please contact
 Oxford Molecular at one of the following sites:
          USA:
                    Toll Free:  1-800-876-9994
                    phone (408) 879-6300   fax (408) 879-6302
                    e-mail: products-: at :-oxmol.com
          UK:       phone  +44 1865 784600 fax +44 1865 784601
                    e-mail:  products-: at :-oxmol.co.uk
 Thank you for your interest and continued support.