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Bruce Palfey brupalf|*|umich.edu wrote: Interchem-Pc has facilities for manual docking. It is free to academics. You would need the auxiliary program for converting PDB files to Interchem format.Sent to CCL by: Bruce Palfey [brupalf^-^umich.edu] Hi I was wondering if people could suggest a good program for manually and interactively building protein-ligand or nucleic acid-ligand complexes. Characteristics of the ideal program are: - Direct. I'd like to be able to grab one molecule and maneuver it into a position I think is interesting using simple, direct mouse and/ or keyboard controls. - Easily loaded. The molecules - either macro or micro - would most likely come from different pdb files, though support of other formats would also be helpful. A minimum of file preparation/conversion is desirable. - Intuitive. The students who pass through my lab should be able to just pick it up and go; we need a tool to support our research, rather than a system to dedicate our efforts to mastering. - Available for common cheap platforms. I'd like to use this on PC's in my lab or on my Mac laptop, or both. - Supports hardware stereo. It seems to me that that's the best way to build. - Free. Or cheap. Or at least a good value worthy of an investment. I welcome all suggestions, and will summarize what I learn. ciao, Bruce Palfey Department of Biological Chemistry University of Michigan Medical School Ann Arbor, MI 48109-0606 All of the Interprobe software is described on: http://www.interprobe.co.uk/inter/interprobe.html This website has a link to the site from where you can download the software. Peter Bladon Interprobe Chemical Services Gallowhill House, Larch Avenue Lenzie, Kirkintilloch Glasgow G66 4HX Scotland |