CCL: How to evaluate the difficulty of synthesize?
- From: "Li Qiang" <chem_liqiang(_)sohu.com>
- Subject: CCL: How to evaluate the difficulty of synthesize?
Sent to CCL by: "Li Qiang" [chem_liqiang#sohu.com]
I are finding a computational method to evaluate(or predict) the
difficulty of synthesize. I have known that SYBYL(Tripos) has a very general
method to evaluate it according to the complexity of molecular structure. But it
is less physical meaning in real organic reaction.
By the way, I hope to know the stability of compound from its structure,
how to evaluate this property?
Thank you for advance!