reduction of van der Waals forces

From: "Carsten Detering" <detering (+ at +) u.washington.edu>
Organization: University of Washington
Subject: reduction of van der Waals forces
Date: Mon, 8 Jul 2002 19:32:10 +0200

Hi CCLers,
 I wonder if it is possible in InsightII to gradually reduce the van der
 Waals forces in an optimization job.
 I have an NMR structure of a chunk of RNA with a ligand, but the structure
 has some bad contacts, hence I have problems docking the ligand in its
 pocket.
 Any suggestions are glady appreciated.
 Thanks a lot in advance
 Carsten
 ~~~~~~~~~~~~~~~~~~~~~~~~~~~
 Carsten Detering
 University of Washington
 Seattle, WA 98195
 email detering (+ at +) u.washington.edu
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