MOE question

 Dear All,
Can anybody tell me how to replace a residue in DNA molecule using MOE software while keeping position of other residues in the DNA molecule constant. This should be simple (but finding out how-to from help files isn't) and I apologize for bothering everybody with such a daft question.
 Thanks a lot for your help,
 Miroslava Cuperlovic-Culf Ph.D.
 Beausejour Medical Research Institute
 37 Providence Street
 Moncton, NB E1C 8X3
 fax: 506-862-4222
 tel: 506-862-4848
 e-mail: miroslavac &$at$&