PowerFit, An Powerful Program for Molecular Fitting



 MICROSIMULATIONS ANNOUNCES RELEASE OF POWERFIT,
 AN POWERFUL PROGRAM FOR MOLECULAR FITTING.
 MAHWAH, New Jersey-August 28, 1996-MicroSimulations Corp., an exciting
 new innovator of molecular design, visualization, and analysis software,
 today announced the release of PowerFit, the second product from it's
 ChemInfo 3D family of applications.
 The first product from this series, AccuModel, is designed for the construction
 of accurate 3D molecular models using the MM3 Force Field and is introduced
 in a seperate posting.
 Complementary to AccuModel, PowerFit enables the chemists to "fit", or
 compare,
 one structure to another. Manual or automated, rigid-body or conformational
 flexible fitting. The fitting potential is based on the work of Kearsley and
 Smith and
 known as "Steric and Electrostatic ALignment (SEAL).
 The global search of the best fit is enabled using Monte Carlo simulated
 annealing
 The user interface is very visual and intuitive. Molecules can be controlled
 manually for detailed visual comparison. User can actually observe the dynamic
 "fitting"
 process.
 Designed for pharmaceutical and biotechnology companies, ChemInfo 3D desktop
 system enables medicinal chemists to visualize, analyze and evaluate chemical
 structures and is essential to efficient, productive molecular research.
 PowerFit is for use on Windows 95, Windows NT, and
 PowerPC and is available for immediate delivery.
 For more information, please visit MicroSimulations' Web site,
 http://www.microsimulations.com
 About MicroSimulations
 Established in 1993, MicroSimulations Corp. offers an exciting suite of
 integrated
 molecular design, visualization, and analysis software used in pharmaceutical,
 chemical, agrochemical, and biotechnology research and development.
 MicroSimulations' innovative products enable individuals, research teams, and
 organizations to leverage intellectual assets by allowing scientist to enhance
 their
 intuition through the use of powerful yet highly cost-effective applications
 designed to
 speed new product discovery.
 --
 Willie Cui, Ph.D.
 Director of Product Development
 MicroSimulations
 478 Green Mountain Road
 Mahwah, NJ 07430
 voice: (201)512-0486
 fax:   (201)512-0489
 http://www.microsimulations.com