From owner-chemistry -8 at 8- ccl.net Sun Nov 23 02:37:00 2008 From: "chupvl chupvl*|*gmail.com" To: CCL Subject: CCL: failed drugs Message-Id: <-38143-081122171942-30780-3FRcnFRPqRi+DtYSc45Xhg()server.ccl.net> X-Original-From: chupvl Content-Transfer-Encoding: 7bit Content-Type: text/plain; charset=ISO-8859-1; format=flowed Date: Sun, 23 Nov 2008 01:19:09 +0300 MIME-Version: 1.0 Sent to CCL by: chupvl [chupvl[#]gmail.com] I think there is no such kind of database, but you can look in some drug-related databases - Prous (now Thomson Reuters) - seems most comprehensive to my mind (no an ad...) - MDL Drug data report (now Symyx) - categories withdrawn and discontinued are exist - PHARMA (http://newmeds.phrma.org/0 - seems only drug in development - etc...there are a lot of drug databases from various vendors as also open access (I think) But for the most interest not the list itslef but the reason for the failure - that database will be priceless :) (eg http://bioinf.charite.de/superdrug/) Yours, Vladimir Chupakhin Moscow State University James T Metz James.Metz]_[Abbott.com wrote: > Sent to CCL by: "James T Metz" [James.Metz .. Abbott.com] > CCL, > > Does anyone maintain a well-curated list of failed drugs or failed drug candidates and when they failed e.g., Phase II, Phase III, market, etc. > > Such a list might be useful for making comparisons to drugs which did not > fail. > > Useful literature references or other sources of information would be much appreciated. > > Regards, > Jim Metz > > Abbott Laboratories> > > >