From chemistry-request- at -ccl.net Fri Jun 17 05:51:03 2005 Received: from mailhost.u-strasbg.fr (mailhost.u-strasbg.fr [130.79.200.155]) by server.ccl.net (8.13.1/8.13.1) with ESMTP id j5H9owFk011725 for ; Fri, 17 Jun 2005 05:50:58 -0400 Received: from sokaris.u-strasbg.fr (sokaris.u-strasbg.fr [IPv6:2001:660:2402::101]) by mailhost.u-strasbg.fr (8.13.1/jtpda-5.5pre1) with ESMTP id j5H8x9sW067933 for ; Fri, 17 Jun 2005 10:59:09 +0200 (CEST) Received: from hit11 (pcf-b315a-hit3.u-strasbg.fr [130.79.85.33]) by sokaris.u-strasbg.fr (8.12.9/jtpda-5.5pre1) with ESMTP id j5H8x7tv061899 for ; Fri, 17 Jun 2005 10:59:09 +0200 (CEST) Received: from [127.0.0.1] by hit11 (PGP Universal service); Fri, 17 Jun 2005 10:55:01 +0100 X-PGP-Universal: processed; by hit11 on Fri, 17 Jun 2005 10:55:01 +0100 Message-ID: <42B28FE5.30205 ^^^ pharma.u-strasbg.fr> Date: Fri, 17 Jun 2005 10:55:01 +0200 From: Mireille Krier User-Agent: Mozilla Thunderbird 1.0 (Windows/20041206) X-Accept-Language: fr, en MIME-Version: 1.0 To: chemistry ^^^ ccl.net Subject: Alpha Helix kink Content-Type: text/plain; charset=ISO-8859-1; format=flowed Content-Transfer-Encoding: 8bit X-Greylist: Sender IP whitelisted, not delayed by milter-greylist-1.6 (mailhost.u-strasbg.fr [IPv6:2001:660:2402::155]); Fri, 17 Jun 2005 10:59:09 +0200 (CEST) X-Antivirus: scanned by sophos at u-strasbg.fr X-Spam-Status: No, score=0.0 required=5.0 tests=none autolearn=failed version=3.0.3 X-Spam-Checker-Version: SpamAssassin 3.0.3 (2005-04-27) on server.ccl.net Dear CCLers, we are looking for a tool that can detect (because not always induced by proline) and measure the angle of an kink in an alpha helix. Any suggestions? We found in the literature SWINK, (Cordes et al., Sansom Group) was developed to estimate the kink and swivel angle of TM small alpha, Greek-helices. Any ideas, if this is available? Many thanks in advance to the community for the any help provided. Mireille Krier -- ----------------------------------------------------------------------- Bioinformatique du midicament, Equipe 5 du Laboratoire de Pharmacochimie et de la communication cellulaire UMR 7081 ULP-CNRS Faculti de Pharmacie 74, route du Rhin - B.P. 60024 F-67401 Illkirch CEDEX, France -----------------------------------------------------------------------