From microsim $#at#$ nis.net Tue Sep 17 01:36:59 1996 Received: from maple.nis.net for microsim |-at-| nis.net by www.ccl.net (8.7.5/950822.1) id AAA12430; Tue, 17 Sep 1996 00:31:19 -0400 (EDT) Received: from FORCE by maple.nis.net with smtp (Smail3.1.28.1 #2) id m0v2rkt-00106QC; Tue, 17 Sep 96 00:27 EDT Message-ID: <323E5434.5DF5 |-at-| nis.net> Date: Tue, 17 Sep 1996 00:33:08 -0700 From: Willie Cui Organization: MicroSimulations X-Mailer: Mozilla 2.02E-KIT (Win95; U; 16bit) MIME-Version: 1.0 To: chemistry(+ at +)www.ccl.net Subject: PowerFit, An Powerful Program for Molecular Fitting Content-Type: text/plain; charset=us-ascii Content-Transfer-Encoding: 7bit MICROSIMULATIONS ANNOUNCES RELEASE OF POWERFIT, AN POWERFUL PROGRAM FOR MOLECULAR FITTING. MAHWAH, New Jersey-August 28, 1996-MicroSimulations Corp., an exciting new innovator of molecular design, visualization, and analysis software, today announced the release of PowerFit, the second product from it's ChemInfo 3D family of applications. The first product from this series, AccuModel, is designed for the construction of accurate 3D molecular models using the MM3 Force Field and is introduced in a seperate posting. Complementary to AccuModel, PowerFit enables the chemists to "fit", or compare, one structure to another. Manual or automated, rigid-body or conformational flexible fitting. The fitting potential is based on the work of Kearsley and Smith and known as "Steric and Electrostatic ALignment (SEAL). The global search of the best fit is enabled using Monte Carlo simulated annealing The user interface is very visual and intuitive. Molecules can be controlled manually for detailed visual comparison. User can actually observe the dynamic "fitting" process. Designed for pharmaceutical and biotechnology companies, ChemInfo 3D desktop system enables medicinal chemists to visualize, analyze and evaluate chemical structures and is essential to efficient, productive molecular research. PowerFit is for use on Windows 95, Windows NT, and PowerPC and is available for immediate delivery. For more information, please visit MicroSimulations' Web site, http://www.microsimulations.com About MicroSimulations Established in 1993, MicroSimulations Corp. offers an exciting suite of integrated molecular design, visualization, and analysis software used in pharmaceutical, chemical, agrochemical, and biotechnology research and development. MicroSimulations' innovative products enable individuals, research teams, and organizations to leverage intellectual assets by allowing scientist to enhance their intuition through the use of powerful yet highly cost-effective applications designed to speed new product discovery. -- Willie Cui, Ph.D. Director of Product Development MicroSimulations 478 Green Mountain Road Mahwah, NJ 07430 voice: (201)512-0486 fax: (201)512-0489 http://www.microsimulations.com