|CCL 19.10.23 PhD position in structure-based drug design in Bergen / Norway|
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To: jobs at ccl.net
Date: Wed Oct 23 06:40:39 2019
Subject: 19.10.23 PhD position in structure-based drug design in Bergen / Norway
At the Faculty of Medicine, Department of Biomedicine in the group of Professor Ruth Brenk (http://www.uib.no/en/rg/brenk ), a PhD-position (100 %) is available for a period of four years. The position is part of the project RESPONsible early Digital Drug Discovery RESPOND3: Towards better computational approaches and responsible innovation strategies in early drug discovery: application to antibiotics and COPD financed by The Research Council of Norway. The RESPOND3 project is part of the Centre for Digital Life Norway (https://digitallifenorway.org/) and is a cross disciplinary collaboration between research groups at the Centre for Advanced studies in Biomedical Innovation Law at the University of Copenhagen, the Department of Computing, Mathematics and Physics at the Western Norway University of Applied Sciences, the Department of Biomedicine at the Faculty of Medicine and at the Department of Chemistry at the Faculty of Mathematics and Natural Sciences at the University of Bergen. In total, the team will be composed of 4 postdocs, 3 PhD students and five principle investigators covering medicinal chemistry, computational chemistry and biology, structural biology, mathematics, and law. The main focus of RESPOND3 will be hit and lead optimization for targets for antibiotics (SAM riboswitch) and chronic obstructive pulmonary disease (proteinase 3) guided by the use of computational methods as well as the development of new scoring functions using machine learning. The entire project is embedded in a responsible research and innovation strategy. The main objectives for the advertised PhD position are - to derive data sets for the development of new scoring functions for protein-ligand interactions with machine learning methods - to retro- and prospectively evaluate the derived scoring functions - to design ligands with improved affinities for the targets in the RESPOND3 project - to supervise master students This PhD project will be conducted in collaboration with the group of Matthias Rarey at the Center for Bioinformatics of University of Hamburg (Germany) implying that this position will involve short research stays in his lab.
More details about the position and instructions on how to apply can be found here: https://www.jobbnorge.no/en/available-jobs/job/177274/phd-position-in-structure-based-drug-designNOTE THAT E-MAIL ADDRESSES HAVE BEEN MODIFIED!!!
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