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Up Directory CCL 19.03.29 Open PhD and Postodc positions for the project - Macromolecular Structures from Single Molecule X-Ray Diffraction Experiments - MPI for Biophysical Chemistry, Gottingen
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Date: Fri Mar 29 11:04:42 2019
Subject: 19.03.29 Open PhD and Postodc positions for the project - Macromolecular Structures from Single Molecule X-Ray Diffraction Experiments - MPI for Biophysical Chemistry, Gottingen
The Max Planck Institute for Biophysical Chemistry is one of the 
largest institutes of the Max Planck Society for the Advancement of 
Science e. V. and conducts basic research to advance knowledge and 
benefit society. Innovative projects and interdisciplinary cooperation 
characterize research within the Max Planck Society.

- You are a physicist or chemist who wants to reveal how life works at the molecular level?
- You know how to combine computer power and theory to solve biological problems?
- You just love doing science?
- You are most welcome!

The Department of Theoretical and Computational Biophysics 
(Prof. Dr. Helmut Grubmuller) invites applications for a position as PhD 
Student or Postdoc (f/m/d)for the project(Code Number 07-19)

- Macromolecular Structures from Single Molecule X-Ray Diffraction Experiments -

to advance structure refinement of single molecule x-ray diffraction data.
In these diffract and destroy experiments, femtosecond x-ray free electron
laser pulses are shotat a single molecule, and the diffraction pattern is 
recorded. Depending on sample size, only very few photons are scattered in
each shot, such that many scattering images have to be combined. The 
analysis is complicated by the fact that for each shot the orientation of 
the sample molecule is random and unknown. We have recently shown that as 
few as three recorded photons per image suffice. You will develop, 
implement, and test with recent experimental data a rigorous Bayesian 
approach, which holds the promise to drastically reduce the number of 
required photons, thus rendering single molecule x-ray structure 
determination feasible. 
Publication: https://www.nature.com/articles/s41467-018-04830-4

The department website https://www.mpibpc.mpg.de/grubmueller provides a 
more general overview of the group's research interests.

Requirements:

The successful candidate for either position has a keen interest and 
strong skills in computational physics, mathematics, and probability 
theory and a strong interest in interdisciplinary collaborative research. 
PhD candidates hold (or expect to complete soon) a Masters or equivalent 
degree; Postdocs hold a PhD or equivalent degree in any of these or a 
related field.

Payment details:

PhD students will have the opportunity to participate in one of several 
available PhD programs, with three years funding and a possibility of 
extension, in collaboration with the University of Gottingen. Masters 
students aiming at a fast track PhD are also welcome. 
The Postdoc position is limited to two years with a possibility of 
extension. Payment and benefits are based on the TVoeD (wage agreement of 
the public sector in Germany) guidelines. The starting date is flexible.

The group language is English, so no German language skills are required  
but its a great opportunity for you to learn German!

The Max Planck Society is committed to increasing the number of individuals
with disabilities in its workforce and therefore encourages applications 
from such qualified individuals.
How to apply:

Interested? Submit your application including cover letter (explaining 
background and motivation), CV, transcripts, and publication record 
preferably via e-mail as one single PDF file to

ausschreibung07-19:-:mpibpc.mpg.de

Max Planck Institute for Biophysical Chemistry
Department of Theoretical and Computational Biophysics
Prof. Dr. Helmut Grubmuller
Am Fassberg 11
37077 Gottingen
Germany
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