CCL Home Page
Up Directory CCL 19.02.19 Senior Scientist/ Principal Scientist/ Director, Computational Chemistry; Cambridge, MA
From: jobs at ccl.net (do not send your application there!!!)
To: jobs at ccl.net
Date: Wed Feb 20 17:50:58 2019
Subject: 19.02.19 Senior Scientist/ Principal Scientist/ Director, Computational Chemistry; Cambridge, MA
COMPANY DESCRIPTION  

Founded in 2016, Foghorn Therapeutics discovers and develops novel 
drugs to treat cancer and other serious medical disorders. The company 
seeks to discover novel therapeutics that target chromatin remodeling 
complexes. 

Foghorn uses a proprietary platform based on revolutionary advances in 
mechanistic understanding of disease. 

POSITION DESCRIPTION

The successful candidate will be joining the computational chemistry 
team at Foghorn Therapeutics. He/she will be expected to drive and 
influence molecular design approaches by applying state of the art 
computational chemistry science. 

Of particular importance is the candidates ability to build strong 
working interactions with medicinal chemists and structural biologists.
The successful candidate will be part of the chemistry team.

Responsibilities include:

- Work in close partnership with medicinal chemists as a united 
compound design team to improve potency, selectivity, and ADME 
properties while minimizing toxicological risk.

- Help to further develop the computational chemistry infrastructure 
and software tools within Foghorn.

- Develop deep understanding of project SAR, and in concert apply 
cutting edge computational chemistry methods to influence team strategy
and compound design, and ultimately positively impact project direction

- Maintain and develop working knowledge of contemporary computational 
chemistry methods and their use in ligand design and data analysis as 
applied to drug design projects.  

QUALIFICATIONS
- Ph.D. in a relevant scientific discipline with at least 4+ years of 
Computational Chemistry experience within a biopharma company. 

- Sufficient experience and confidence to operate independently as the 
computational chemistry resource within the project team and represent 
computational chemistry in a variety of cross-functional contexts. 

- Strong familiarity with a wide range of current computational 
chemistry software tools.

- Expert molecular designer with creativity & the ability to design 
ligands & libraries; utilizes tools to evaluate/prioritize ideas.

- Highly collaborative, team oriented professional with a passion for
drug design.  

- Experience with ligand and structure based computational chemistry 
activities. 

- A working knowledge of synthetic chemistry to enable independent 
compound design of synthetically tractable targets.

- Model building and method development experience, informatics 
experience, and familiarity with high throughput screening, preferred 
but not required.
Please apply using the link below: 

 https://foghorntherapeutics.applytojob.com/apply/J1kYNVPCLm/Senior-Scientist-Princi
NOTE THAT E-MAIL ADDRESSES HAVE BEEN MODIFIED!!!
All @ signs were changed to !A! to fight spam. Before you send e-mail, you need to change !A! to @
For example: change joe!A!big123comp.com to joe@big123comp.com
Please let your prospective employer know that you learned about the job from the Computational Chemistry List Job Listing at http://www.ccl.net/jobs. If you are not interested in this particular position yourself, pass it to someone who might be -- some day they may return the favor.
Modified: Wed Feb 20 22:50:58 2019 GMT
Page accessed 1021 times since Wed Feb 20 23:44:45 2019 GMT