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Up Directory CCL 19.01.23 Computational Drug Hunter, Orion Corporation, Espoo, Finland
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Date: Wed Jan 23 06:17:43 2019
Subject: 19.01.23 Computational Drug Hunter, Orion Corporation, Espoo, Finland
Orion is a globally operating Finnish company listed on the Helsinki
Stock Exchange. Orion develops, manufactures and markets human and
veterinary pharmaceuticals and active pharmaceutical ingredients for
global markets. Orion's pharmaceutical innovations are created within its
R&D organization, including e.g. non-clinical research, clinical
development, formulation development and medical affairs. The organization
employs top professionals in the field of drug molecule development and

Global Medicine Design contributes to the drug discovery process of
Orion R&D from target validation all the way to the candidate nomination.
We are responsible for translating new drug targets to the small molecule
therapeutics together with other line functions. Our scientists in biology,
chemistry and computer-aided medicine design are key players in the
multiple research programs driven by Orion's three therapy areas; CNS,
Oncology and Rare Diseases. We also support biologics discovery with our
core competences.

Description of position:
In order to maintain and enhance our capabilities we are now searching for
a new enthusiastic Drug Hunter to join our Computer Aided Medicine Design

The Computational Drug Hunter will work in our drug discovery R&D projects
applying various computational tools and develop computer-aided drug design
methods and processes. This includes both ligand- and structure-based
design, protein modelling, structure-activity data analysis and knowledge
extraction from a variety of in-house and public sources of experimental
& computational data and literature. The Drug Hunter will collaborate
closely with a broad range of scientists including other modellers,
medicinal chemists, pharmacologists and biologists.

The position is full-time and you will be based in Espoo, Finland.

We offer:
We offer you great, highly professional & experienced colleagues
and the opportunity to show your talent and challenge yourself with
interesting tasks in a modern multidisciplinary environment.
Orion as the #1 research-based pharma company in Finland provides
plenty of possibilities for personal development to become a true
pharmaceutical industry expert. Generous health and welfare benefits are
available, as well as support for international relocation.


- Ph.D. from a suitable field, e.g. computational chemistry,
bioorganic chemistry, biophysics
- Two years of post-doctoral or industrial experience relevant for
drug discovery is appreciated
- Experience in computational structure design, knowledge of
state-of-the-art ligand- and structure-based methods and their
applications for medicine design
- Good general understanding of the drug discovery process
(e.g. medicinal chemistry, pharmacology, cell biology)
- In-depth experience in at least one of the following fields:
Physics-Based methods (modelling and/or experimental) for medicine design,
Application of Deep learning for Drug Discovery,
Protein / Antibody Modelling, Molecular Dynamics simulations of

Experience with modelling software (preferably Schrdinger), data
pipelining tools (e.g. Knime) andprogramming/scripting/data analysis/data
visualization (e.g. Python/R) is desirable.

For additional information about the position, please contact
Julius Sipila, Head of Computer Aided Medicine Design,
tel +358 50 966 2605 during the following times:
- Wednesday, January 30 at klo 13-17 (UTC+2)
- Wednesday, February 6 at 13-17 (UTC+2)
Please, send your application by February 12, 2019 through our webpage
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Modified: Wed Jan 23 11:17:45 2019 GMT
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