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Up Directory CCL 16.12.21 Early Stage Researcher (ESR) position (with optional PhD program) at ProtoQSAR (Spain)
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Date: Wed Dec 21 04:27:46 2016
Subject: 16.12.21 Early Stage Researcher (ESR) position (with optional PhD program) at ProtoQSAR (Spain)
ProtoQSAR is a company founded in 2012 and located in the Science Park
of the University of Valencia (Spain). Our activity consists in the
application of computational methods to natural or synthetic chemical
compounds, in order to predict and optimize their physico-chemical, 
biological and/or (eco)toxicological properties. Main working areas: 
pharmacy, veterinary, cosmetic, agrochemical,  etc.

Our competences include chemoinformatics (QSAR, grouping, Read-across, 
etc.), management and analysis of chemical data, computational 
toxicology, molecular modelling (docking, pharmacophores, virtual screening). 
We have extensive experience in both the academic and industrial sides,
with more than 80 publications in national and international scientific journals, 
and over 50 seminars and presentations at professional conferences.

For further information about us and our activities, please see our web 
page: http://www.protoqsar.com

ProtoQSAR is offering a unique opportunity for an Early Stage Researcher (ESR) 
to undertake research in the framework of the project PROTECTED (PROTECTion 
against Endocrine Disruptors; detection, mixtures, health effects, risk assessment 
and communication). The ESR will be funded for 3 years through the prestigious 
Marie Skodowska-Curie Actions (MSCA) Innovative Training Network (ITN)
programme, an initiative by the European Commission (EC) to foster academic-industrial 
collaboration in the frame of an innovative and entrepreneurial PhD training program.

More information about the MSCA-ITN program and the PROTECTED project at:
http://ec.europa.eu/research/mariecurieactions/index_en.htm
https://euraxess.ec.europa.eu/jobs/154993
http://protected.eu.com/index.html



Job description

The aim of the ESR at ProtoQSAR will be to develop computational predictive models 
for the effects of endocrine disruptors (EDs) and their mixtures through the use 
of advanced in silico techniques, mainly predictive quantitative structure-activity 
relationships (QSAR) models.

Information on chemicals in epidemiology studies, natural hormones levels during 
foetal development will be provided by other partners of the ITN, for predictive 
computational development and validation purposes, and real life mixtures will also 
be generated with the same objective. Once all the necessary information is compiled, 
the ESR will apply different chemo-informatics approaches to produce models for EDs 
and their mixtures. Experimental validation of the robustness and predictive ability 
of the models will also be performed. Finally, virtual screening (VS) tools will be 
applied for searching alternatives to chemicals with ED concern.



Key responsibilities of the ESR

- To manage and carry out an independent research project in close collaboration 
  with the ProtoQSAR staff and collaborators. 
- To actively participate in research and training activities within the ProtoQSARs group.
- To contribute to preparation of reports.
- To contribute to writing articles for scientific journals.
- To disseminate research results in the scientific community (via international conferences) 
  and in the non-scientific community (via outreach and public engagement).
- To engage in additional training events and secondments within the PROTECTED network.
- Optionally, the ESR can follow in parallel a PhD program related to the PROTECTED work 
  at ProtoQSAR, financed by the company with the project budget allocated for research activities.



Candidate background

- 1st class or 2.1 Honours Degree or equivalent in Chemistry, Pharmacology, Toxicology 
  or a related discipline.
- Demonstrable knowledge or basic background on chemoinformatics and molecular modelling. 
- Demonstrable knowledge and interest in medicinal chemistry and drug discovery.
- Be in the first 4 years (full-time equivalent) of his/her research career and not yet 
  have been awarded a doctorate. This 4-year period is measured from the date of obtaining 
  the degree which would formally entitle to embark on a doctorate. 
- Be a national of any country and must not have resided or carried out their main activity in Spain 
  for more than 12 months in the 3 years immediately prior to the selection for this position.
- Be willing and able to perform secondments or participate in training programs at the 
  facilities of other consortium members such as The Netherlands, Norway, France, Chile, 
  Belgium and the United Kingdom. 
- For candidates wishing to follow a PhD programme in parallel, they have to be eligible 
  and qualified for enrolment in the PhD programme at the University of their choice (preferably at 
  the University of Valencia, Spain, which is located close to the ProtoQSAR offices). 



Terms of appointment

MSCA-ITN offers an attractive salary and working conditions. 
A unique feature of MSCA-ITN is that during the PhD research, ESR PhD students will be 
given the opportunity to perform secondments at the facilities of other consortium members. 
ESR PhD students will benefit from a dedicated training program in the various fields 
of expertise of the consortium partners. Salary is complemented with a mobility allowance.



Person specifications and qualities

- Strong analytical and problem solving skills
- Ability to logically conceptualize and summarize the research findings
- Advanced analytical skills 
- Excellent verbal and writing communication skills
- Ability to interact with colleagues and staff
- Demonstrable intellectual ability.
- Ability to communicate complex information clearly. 
- Ability to organise resources, manage time and meet deadlines
If interested, please send Curriculum Vitae, a letter of motivation and two-three 
recommendation letters to info^^protoqsar.com before the closing application 
deadline Monday 16th January 2017.
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