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Up Directory CCL 08.07.09 Computational Chemist/ Modeler/ Computational Structural Biologist - Singapore
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To: jobs at ccl.net
Date: Wed Jul 9 19:39:57 2008
Subject: 08.07.09 Computational Chemist/ Modeler/ Computational Structural Biologist - Singapore
Codexis is a leading developer of proprietary biocatalysts that the company believes have the potential 
to revolutionize chemistry-based manufacturing processes across a variety of industries. The company has
used its technology platform to enable biocatalyst-based commercial-scale drug manufacturing processes 
and delivered biocatalysts and drug products to some of the worlds leading pharmaceutical companies. 
Codexis has a funded collaboration in the biofuels market, and the company is pursuing funded collaborations 
in several other bioindustrial markets, including carbon management, water treatment and chemicals.

Title: Computational Chemist/ Modeler/ Computational Structural Biologist 

Responsibilities:
Your focus will be on new and challenging innovations in the areas of computational enzyme design and the 
understanding of enzyme binding, catalysis, and selectivity in the context of simulations.

Possible relevant research experience would include computational enzyme design, applying computational methods 
(e.g. docking, homology modeling, conformational analysis, molecular dynamics to the prediction of enzyme structures, 
binding, catalysis, and selectivity. This candidate should have a strong understanding of bioinformatics, enzymology, 
protein engineering, and directed evolution. Knowledge about molecular biology or QM/MM would be beneficial.

The qualified candidate must understand molecular modeling software (MOE, Accelrys, SYBYL, etc.), bioinformatics software, 
and online databases (BLAST, BRENDA, RCSB PDB, ExPASy, etc.). Expertise in scientific programming and scripting is a plus.

Requirements:
        - Ph.D. or work experience equivalent in Computational Chemistry or related field. Experience in the biotech industry 
          is a plus, as is an understanding of LIMS systems.
	- A proven intellectual ability and an outstanding scientific track record in the candidates field of expertise.
	- Proven expertise in computational enzyme design and the understanding of enzyme binding, catalysis, and selectivity.
	- Active recent experience in computational tools for macro and small molecule modeling and a quick learner of 
          computational software. Knowledge of scripting languages is a plus.
	- Strong interpersonal and communication skills (both written and verbal).
	- Strong problem solving skills and the ability to work on multiple projects in a fast-paced and goal-oriented 
          team environment.
The position comes with competitive compensation and a great benefits package. For more information about our plans of the 
future, and to be considered for this career opportunity, please visit www.codexis.com.
To apply visit our careers site at www.codexis.com
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