Work for a company that is making a difference in the fight against
cancer.  SuperGen, Inc. www.supergen.com is dedicated to finding faster, less
expensive, and more efficacious methods for the discovery and development of
drugs.  We are looking for a motivated and dedicated professional who is
seeking to broaden their horizons and take on a new set of challenges.

This position is responsible for highly motivated and results oriented
candidates who have strong knowledge of computational chemistry principles
and applications. The candidate must display and continue to develop a broad
range of structural and computational biology experience.

Essential duties and responsibilities:
The primary responsibilities of this position are for discovery and
implementation of novel computational methods, analyses, and workflows that
ultimately accelerate the drug design process and model specific inhibitors
against the given targets. Research activities include identification of
novel methods for virtual screening, lead identification, structure-based
design, ab-initio molecular dynamics, binding energy determinations, scoring
function design used to study the interactions of the small
molecules/proteins, and/or in silico predictive methods for improvement of
ADMET characteristics. The work involves collaboration with experimentalists,
synthetic/medicinal chemists for lead optimization/modifications and testing
of the designed structures.

Minimum Requirements:

 The position requires a Ph.D. in a Computational Chemistry-based discipline
 or equivalent, plus 2+ years of industrial or post-doctoral experience.

 Sound knowledge of computational chemistry principles/applications and on how
 to implement these techniques to pharmaceutical drug discovery research
 projects.

 Expertise in conducting protein structure predictions, small
 molecule/protein-protein docking, virtual screening, molecular dynamics
 simulation, QM/MM methods, lead optimization principles, and downstream
 property optimizations techniques that enable successful drug candidates. 

 Prior experience/knowledge in Structural Biology, Medicinal/Organic chemistry
 is a plus.

 Technical qualifications include good scientific computing experience with
 programming languages such as Java or C++, relational database tools,
 operating systems such as Linux/Unix and/or web application development
 tools. 

 Ability to learn new software easily, work independently and as part of
 a multi-disciplinary team with a high level of personal, professional
 drive and initiative, excellent interpersonal, presentation and
 problem-solving skills are required.

Benefits: We provide a comprehensive benefits package to include
medical, vision, dental, short and long term disability, group term
life, 401(k) and an Employee Assistance

Interested candidates are encouraged to apply at 
http://www.supergen.com