From: chemistry-request at ccl.net <br />
To: chemistry-request at ccl.net<br />
Date: Fri Feb  1 09:37:36 2013<br />
Subject: 13.06.19 <span class="fancysmall">CHI's Structure-Based Drug Design</span><br />

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June 19-21, 2013,
The Revere Hotel, Boston, MA
<a href="http://www.healthtech.com/sbd/"
target="_blank">http://www.healthtech.com/sbd/</a>

At CHI/Bio-IT World's thirteenth annual Structure-Based Drug Design
conference, you will hear about developments in insilico technology, as
well as experimental approaches useful for accurately predicting and
modeling the structures of proteins in structure-based drug design
efforts. In addition, examples of successful applications of such
technology approaches to genome-to-drug lead investigations will be
addressed.

KEYNOTE PRESENTATION:

<b>Drugging the Undruggable:
Transforming Nature's &alpha;-Helix into Breakthrough Medicines</b>
Tomi Sawyer, Ph.D., CSO, Aileron Therapeutics

<b>Exploiting Solvent Effects in Drug Design and Optimization</b>
Christopher R. Corbeil, Ph.D., Research Scientist, Chemical Computing Group

<b>Determination of Binding Poses, Kinetics and Energetics in Fragment-Based
Design</b>
Gianni De Fabritiis, Ph.D., Computational Biophysics Laboratory (GRIB-IMIM),
Universitat Pompeu Fabra, Barcelona Biomedical Research Park (PRBB)

<b>Visually Informed, Interactive Lead Optimization</b>
Carsten Detering, Ph.D., CEO, BioSolveIT

<b>Case Histories of Recent Fragment-Based Drug Discovery Projects</b>
Christopher Murray, Ph.D., Director, VP Discovery Technology,
Astex Pharmaceuticals

<b>Incorporating Ligand Polarisation in Binding Free Energy Calculations</b>
Jonathan W. Essex, Ph.D., Head, Computational Systems Chemistry, Chairman,
Institute for Complex Systems Simulation (ICSS), School of Chemistry,
University of Southampton
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