From owner-chemistry@ccl.net Thu Apr 2 04:50:00 2009 From: "Serdar Badoglu sbadoglu!A!gazi.edu.tr" To: CCL Subject: CCL:G: overtone and combination bands Message-Id: <-38988-090402044747-8000-vUj9ao/bmCOvsyPgPzfTGQ^^server.ccl.net> X-Original-From: "Serdar Badoglu" Date: Thu, 2 Apr 2009 04:47:42 -0400 Sent to CCL by: "Serdar Badoglu" [sbadoglu a gazi.edu.tr] Hi to all CCLers. I have some extra peaks in my experimental IR spectrum which are not available in Gaussian calculated spectrum. I know that these calculated bands are only the fundamentals but somehow I need to compute the overtones and combinations bands of my molecule, preferably in Gaussian03. Is it possible, and how? From owner-chemistry@ccl.net Thu Apr 2 05:30:01 2009 From: "shabbir muhammad shabbir3790]=[hotmail.com" To: CCL Subject: CCL: other forum besides CCL Message-Id: <-38989-090402041352-1833-/skAWjy8bnoM1S8PLeKpsw],[server.ccl.net> X-Original-From: "shabbir muhammad" Date: Thu, 2 Apr 2009 04:13:48 -0400 Sent to CCL by: "shabbir muhammad" [shabbir3790*|*hotmail.com] Dear ccl users, Is there any other forum for discussion of computational chemistry problems as is CCL....? Thanks From owner-chemistry@ccl.net Thu Apr 2 07:51:01 2009 From: "Ol Ga eurisco1..pochta.ru" To: CCL Subject: CCL: other forum besides CCL Message-Id: <-38990-090402073803-32240-ZsxcWKXTt4YFD/so/1XTvA|a|server.ccl.net> X-Original-From: "Ol Ga" Date: Thu, 2 Apr 2009 07:37:59 -0400 Sent to CCL by: "Ol Ga" [eurisco1]=[pochta.ru] Dear shabbir muhammad, pls, take a look http://iopenshell.usc.edu/forum/ But ccl is the most powerfull :-) Sincerely, Ol Ga > Sent to CCL by: "shabbir muhammad" [shabbir3790*|*hotmail.com] > Dear ccl users, > > Is there any other forum for discussion of computational chemistry problems as is CCL....? > Thanks From owner-chemistry@ccl.net Thu Apr 2 08:25:01 2009 From: "Loeprecht, Bjoern loeprech|tripos.com" To: CCL Subject: CCL: Monitors for CADD/molecular modelling Message-Id: <-38991-090402073743-32170-OzHR9xD+IVoTF4Ip2ROj2w*|*server.ccl.net> X-Original-From: "Loeprecht, Bjoern" Content-class: urn:content-classes:message Content-Transfer-Encoding: quoted-printable Content-Type: text/plain; charset="iso-8859-1" Date: Thu, 2 Apr 2009 06:07:14 -0500 MIME-Version: 1.0 Sent to CCL by: "Loeprecht, Bjoern" [loeprech . tripos.com] There are some more stereo monitor options: http://www.planar3d.com/ http://www.netmax.de/public/displays/de/realmax/ here is a 3D expert company which you may ask about other possibilities: http://www.3dims.de/ =20 -- Dr. Bj=F6rn Loeprecht Senior Application Scientist Tripos - A Certara(tm) Company =20 SYBYL 8.1, including support for Mac OS X, now available _______________________________________ Tripos Int. Spain S.L. - Zweigniederlassung Deutschland Martin-Kollar-Stra=DFe 17 * D-81829 M=FCnchen * Germany Amtsgericht M=FCnchen HRB 168550 * USt-Nr./VAT-No. 26 219 8465 2 * = USt-ID-Nr./VAT-ID-No.DE255705780 Tel: +49-89-451030-13 * Fax: +49-89-451030-30 Email: loeprecht{:}tripos.com * Web: http://www.tripos.com =20 Hauptniederlassung: Tripos International Spain, S.L. Gran Via, 45, 6=AA planta * 48011 Bilbao (Vizcaya) * Spain Business Register of Biscay in volume 4,787, Folio 153, sheet number = VI-48,095 * VAT-ID-No.ESB95455671 Board of Directors: Christopher G. Nicholson * Jos=E9 F. Elorriaga Ancin = * Dewey W. Chambers * Alexander R. Slusky _________________________________________________________________________= _______________________ This electronic message transmission contains information from Tripos = which may be confidential and proprietary to Tripos or a Tripos = customer. The information is intended for the use of the addressee named = above. If you are not the addressee be aware that any disclosure, = copying, distribution or use of the contents of this electronic message = is prohibited. -----Original Message----- > From: owner-chemistry+loeprecht=3D=3Dtripos.com{:}ccl.net = [mailto:owner-chemistry+loeprecht=3D=3Dtripos.com{:}ccl.net] On Behalf Of = David Clark david.clark- -argentadiscovery.com Sent: Tuesday, March 31, 2009 1:42 PM To: Loeprecht, Bjoern Subject: CCL: Monitors for CADD/molecular modelling Sent to CCL by: "David Clark" [david.clark|argentadiscovery.com] Hi I've got an ageing SGI CRT display that may be coming to the end of its = life. Can anyone suggest a modern replacement (LCD) that would be suitable for = CADD/modelling tasks including stereo-vision with Stereographics? Many thanks David -=3D This is automatically added to each message by the mailing script = =3D-http://www.ccl.net/cgi-bin/ccl/send_ccl_messageSubscribe/Unsubscribe:=20Job: http://www.ccl.net/jobs=20http://www.ccl.net/spammers.txt From owner-chemistry@ccl.net Thu Apr 2 09:15:00 2009 From: "TOULHOAT Herve Herve.TOULHOAT[A]ifp.fr" To: CCL Subject: CCL: Coordinates for Structure I and Structure II hydrates Message-Id: <-38992-090402034454-30792-CSQq6Bdg7LdhL0UAOZU43A++server.ccl.net> X-Original-From: "TOULHOAT Herve" Content-class: urn:content-classes:message Content-Transfer-Encoding: quoted-printable Content-Type: text/plain; charset="iso-8859-1" Date: Thu, 2 Apr 2009 09:10:53 +0200 MIME-Version: 1.0 Sent to CCL by: "TOULHOAT Herve" [Herve.TOULHOAT{=}ifp.fr] Dear Ramachandran, try for recent data:=20 Gas Hydrate Single-Crystal Structure Analyses Michael T. Kirchner, Roland Boese, W. Edward Billups, and Lewis R. Norman J. Am. Chem. Soc., 2004, 126 (30), 9407-9412* DOI: 10.1021/ja049247c * Publ= ication Date (Web): 13 July 2004 And the corresponding 247245 to 247249 *.cif files you can retrieve rthroug= h: http://www.ccdc.cam.ac.uk/cgi-bin/catreq.cgi Sincerely yours, Professor Herv=E9 Toulhoat Deputy Scientific Director Exploratory Research Manager Director of Doctoral Studies Institut Fran=E7ais du P=E9trole Tel +33 1 47 52 73 50 Fax +33 1 47 52 70 36 e-mail: herve.toulhoat^ifp.fr Visit IFP web site: Computational Chemistry and Catalysis: -----Message d'origine----- De : owner-chemistry+herve.toulhoat=3D=3Difp.fr^ccl.net [mailto:owner-chemistry+herve.toulhoat=3D=3Difp.fr^ccl.net]De la part de Ramachandran Chelat rcchelat{:}rediffmail.com Envoy=E9 : mercredi 1 avril 2009 17:00 =C0 : TOULHOAT Herve Objet : CCL: Coordinates for Structure I and Structure II hydrates Sent to CCL by: "Ramachandran Chelat" [rcchelat**rediffmail.com] Dear CCL friends, I am looking for the coordinates for Structure I and Structure II in which = gas hydrates are forming. Can you please help me to get coordinates or ref= erences of the same for a unit cell of these structures Thanks in advance Ramachandran -=3D This is automatically added to each message by the mailing script =3D-http://www.ccl.net/cgi-bin/ccl/send_ccl_messageSubscribe/Unsubscribe:=20Job: http://www.ccl.net/jobs=20http://www.ccl.net/spammers.txt__________________________ Ce message (et toutes ses pi=E8ces jointes =E9ventuelles) est confidentiel = et =E9tabli =E0 l'intention exclusive de ses destinataires. Toute utilisati= on de ce message non conforme =E0 sa destination, toute diffusion ou toute = publication, totale ou partielle, est interdite, sauf autorisation expresse= . L'IFP d=E9cline toute responsabilit=E9 au titre de ce message. This message and any attachments (the message) are confidential and intende= d solely for the addressees. Any unauthorised use or dissemination is prohi= bited. IFP should not be liable for this message. Visitez notre site Web / Visit our web site : http://www.ifp.fr __________________________ From owner-chemistry@ccl.net Thu Apr 2 09:51:01 2009 From: "Yu-Chang Chang ycchang]~[chem.sinica.edu.tw" To: CCL Subject: CCL:G: geometry optimization with large maximum force Message-Id: <-38993-090402035352-31794-rqHyMoF11oPF6LdbF5wy0Q_._server.ccl.net> X-Original-From: "Yu-Chang Chang" Date: Thu, 2 Apr 2009 03:53:47 -0400 Sent to CCL by: "Yu-Chang Chang" [ycchang[a]chem.sinica.edu.tw] Dear all, I recently encounter one problem of geometry optimization using G03: Item Value Threshold Converged? Maximum Force 0.002524 0.000450 NO RMS Force 0.000265 0.000300 YES Maximum Displacement 0.001324 0.001800 YES RMS Displacement 0.000201 0.001200 YES Predicted change in Energy=-1.162734D-06 It seems that the PES is quite sharp near the local minimum. I have tried the keywords such as iop(1/8=1), opt=gdiis or opt=calcfc. Does anyone have any suggestion for me? Your response in very much appreciated. Yu-Chang Chang Institute of Chemistry Academia Sinica, Taiwan E-mail: ycchang!A!chem.sinica.edu.tw From owner-chemistry@ccl.net Thu Apr 2 11:41:01 2009 From: "Sten Nilsson Lill stenil#%#chem.gu.se" To: CCL Subject: CCL:G: geometry optimization with large maximum force Message-Id: <-38994-090402112321-11015-S7SFPOIkbJSa/zVUc7rYZw-.-server.ccl.net> X-Original-From: "Sten Nilsson Lill" Content-Transfer-Encoding: 8bit Content-Type: text/plain;charset=iso-8859-1 Date: Thu, 2 Apr 2009 16:45:07 +0200 (CEST) MIME-Version: 1.0 Sent to CCL by: "Sten Nilsson Lill" [stenil:+:chem.gu.se] Dear Yu-Chang Chang, in a few cases when nothing else gets the structure to converge I have used opt=newton and that has solved the problem. You can find it in the G03 manual. Hope that helps! Regards, Sten > > Sent to CCL by: "Yu-Chang Chang" [ycchang[a]chem.sinica.edu.tw] > Dear all, > > I recently encounter one problem of geometry optimization using G03: > > Item Value Threshold Converged? > Maximum Force 0.002524 0.000450 NO > RMS Force 0.000265 0.000300 YES > Maximum Displacement 0.001324 0.001800 YES > RMS Displacement 0.000201 0.001200 YES > Predicted change in Energy=-1.162734D-06 > > It seems that the PES is quite sharp near the local minimum. > I have tried the keywords such as iop(1/8=1), opt=gdiis or opt=calcfc. > Does anyone have any suggestion for me? > Your response in very much appreciated. > > Yu-Chang Chang > Institute of Chemistry > Academia Sinica, Taiwan > E-mail: ycchang * chem.sinica.edu.tw> > > Ph. D. Sten Nilsson Lill Dep. of Chemistry University of Gothenburg Kemigården 4 S-412 96 Göteborg, Sweden Phone: +46-31-772 2873 Fax: +46-31-772 3840 E-mail: stenil_._chem.gu.se Alternative e-mail: stenil_._physto.se From owner-chemistry@ccl.net Thu Apr 2 12:52:01 2009 From: "Gergana Koleva ohtgk:-:chem.uni-sofia.bg" To: CCL Subject: CCL:G: Reaction field in G03 Message-Id: <-38995-090402121824-3114-chKzFRpKWzla0G5wkLXr3g+*+server.ccl.net> X-Original-From: "Gergana Koleva" Date: Thu, 2 Apr 2009 12:18:19 -0400 Sent to CCL by: "Gergana Koleva" [ohtgk-.-chem.uni-sofia.bg] Dear CCL'ers, I am trying to run reaction field calculations with G03 with acetic acid as the solvent, using the scrf=pcm or scrf=cpcm. This solvent is not specified in G03, so I need to specify it explicitly in the input. However, I have tried in a variety of ways (interpretations of the web manual) to specify it by eps=6.15 with no success. For practical reasons I will not the show them all here. A corrected input that works would be perfect! :-) From owner-chemistry@ccl.net Thu Apr 2 17:48:01 2009 From: "Lukasz Cwiklik cwiklik#%#gmail.com" To: CCL Subject: CCL: Coordinates for Structure I and Structure II hydrates Message-Id: <-38996-090402174643-2104-96WeYYwiG8S+wmNZyZnczw++server.ccl.net> X-Original-From: Lukasz Cwiklik Content-Transfer-Encoding: quoted-printable Content-Type: text/plain; charset=ISO-8859-1 Date: Fri, 3 Apr 2009 00:46:15 +0300 MIME-Version: 1.0 Sent to CCL by: Lukasz Cwiklik [cwiklik{}gmail.com] On Wed, Apr 1, 2009 at 6:00 PM, Ramachandran Chelat rcchelat{:}rediffmail.com wrote: > > Sent to CCL by: "Ramachandran =A0Chelat" [rcchelat**rediffmail.com] > Dear CCL friends, > I am looking for the coordinates for Structure I and Structure II in whic= h gas hydrates are forming. =A0Can you please help me to get coordinates or= references of the same =A0for a unit cell of these structures > Thanks in advance Dear Ramachandran, I have one general comment to your question. It is quite likely that you are aware of what I want to say but let me put it clearly since it was a problem for me once. Depending on the problem under study one should keep in mind that under 'normal' conditions clathrate hydrates exhibit proton disorder (just like Ih ice does) so protons (or rather hydrogen atoms) in these materials do not form periodic structure. If one wants to perform, for instance, MD simulations for clathrate hydrates, he/she has to generate/find proton positions randomly but still fully obeying the completeness of H-bonds network. Another problem that arises is that the generated proton configuration should give a zero average dipole moment. Proton disorder can be a source of quite a lot of problems for simulations and modeling of ice or ice-related systems. Best regards, Lukasz --=20 Lukasz Cwiklik http://cwiklik.wordpress.com From owner-chemistry@ccl.net Thu Apr 2 18:28:01 2009 From: "Roman D Gorbunov rgorbuno(-)aecom.yu.edu" To: CCL Subject: CCL:G: Why "Eigenvalues" in the Gaussian output file are so large? Message-Id: <-38997-090402182652-24030-4s151BQXxUrvrjgJG9iAzw^server.ccl.net> X-Original-From: "Roman D Gorbunov" Date: Thu, 2 Apr 2009 18:26:48 -0400 Sent to CCL by: "Roman D Gorbunov" [rgorbuno ~~ aecom.yu.edu] Dear CCL Subscribers, In my Gaussian output file I found the following lines: Eigenvalues --- 0.61543 0.75911 0.790561000.000001000.00000 Eigenvalues --- 1000.000001000.000001000.000001000.000001000.00000 Eigenvalues --- 1000.000001000.000001000.000001000.000001000.00000 It looks suspicious. However I still have the "Normal termination". Does anybody know what these "Eigenvalues" means and why they are equal to "1000.00000"? Could these lines be an indication that something wrong with my calculations or I should not wary about that? Thank you in advance, Roman From owner-chemistry@ccl.net Thu Apr 2 19:03:01 2009 From: "Roman D Gorbunov rgorbuno]~[aecom.yu.edu" To: CCL Subject: CCL:G: "Final forces over variables" and "-nan" in the Gaussian output. Message-Id: <-38998-090402183457-29959-c0A+02B88kAoo0HagHVThg(0)server.ccl.net> X-Original-From: "Roman D Gorbunov" Date: Thu, 2 Apr 2009 18:34:54 -0400 Sent to CCL by: "Roman D Gorbunov" [rgorbuno(~)aecom.yu.edu] Dear CCL Subscribers, In my Gaussian output file after the "Final forces over variables, Energy=-1.78040761D+03:" there are a lot of "-nan". Does anybody know what does it means? Thank you in advance, Roman From owner-chemistry@ccl.net Thu Apr 2 19:42:01 2009 From: "Roman D Gorbunov rgorbuno%x%aecom.yu.edu" To: CCL Subject: CCL:G: Why fixed internal coordinates are not constant? Message-Id: <-38999-090402184636-8035-dV52eDtOJryM05l2RRF0Xw-.-server.ccl.net> X-Original-From: "Roman D Gorbunov" Date: Thu, 2 Apr 2009 18:46:31 -0400 Sent to CCL by: "Roman D Gorbunov" [rgorbuno/./aecom.yu.edu] Dear CCL Subscribers, I found out that internal coordinates which were supposed to be fixed during a geometry optimization are not fixed. Pleas, can anybody help me? My Gaussian input file looks like that: %NProcShared=4 %RWF=f1,245MW,f2,245MW,f3,245MW,f4,245MW,f5,245MW,f6,245MW,f7,245MW,f8,245MW,f9,245MW,f10,-1 %mem=2000MB #B3LYP/6-31G* GFINPUT IOP(7/33=1) Opt=(ModRedundant,MaxCycle=1000) ---------- 0 1 n c 1 cn2 c 2 cc3 1 ccn3 n 3 nc4 2 ncc4 1 dih4 c 4 cn5 3 cnc5 2 dih5 ............................................... h 101 hc107 83 hcn107 79 dih107 h 102 hc108 84 hcn108 80 dih108 cn2 1.384155 cc3 1.399428 ccn3 110.943 nc4 1.373309 ............................................... hcn108 109.471 dih108 60.000 36 37 F 37 56 F 7 36 37 38 F 38 37 56 57 F 7 36 F 37 38 F 56 57 F 6 7 36 F 37 38 39 F 56 57 58 F 2 6 7 36 F 37 38 39 40 F 56 57 58 59 F Probably I have to mention that I use dummy atoms to set my constrains. For example I fix the distance between 2 dummy atoms but I see that during the geometry optimization these distance increases. I will appreciate any help, Roman From owner-chemistry@ccl.net Thu Apr 2 21:42:01 2009 From: "xunlei ding dingxunlei_+_gmail.com" To: CCL Subject: CCL:G: Why fixed internal coordinates are not constant? Message-Id: <-39000-090402204010-23642-3CmBINx5+5ErqDM7XzLipw|-|server.ccl.net> X-Original-From: xunlei ding Content-Transfer-Encoding: quoted-printable Content-Type: text/plain; charset=GB2312 Date: Fri, 3 Apr 2009 08:39:56 +0800 MIME-Version: 1.0 Sent to CCL by: xunlei ding [dingxunlei*o*gmail.com] I think the first thing you could try is to test on a small molecule using the same format you used but without dummy atoms. This will identify whether your problem is because of dummy atoms or the fo= rmat. Best wishes, Ding 2009/4/3 Roman D Gorbunov rgorbuno%x%aecom.yu.edu = : > > Sent to CCL by: "Roman D Gorbunov" [rgorbuno/./aecom.yu.edu] > Dear CCL Subscribers, > > I found out that internal coordinates which were supposed to be fixed dur= ing a geometry optimization are not fixed. Pleas, can anybody help me? > > My Gaussian input file looks like that: > > %NProcShared=3D4 > %RWF=3Df1,245MW,f2,245MW,f3,245MW,f4,245MW,f5,245MW,f6,245MW,f7,245MW,f8,= 245MW,f9,245MW,f10,-1 > %mem=3D2000MB > #B3LYP/6-31G* GFINPUT IOP(7/33=3D1) Opt=3D(ModRedundant,MaxCycle=3D1000) > > ---------- > > 0 1 > n > c 1 cn2 > c 2 cc3 1 ccn3 > n 3 nc4 2 ncc4 1 dih4 > c 4 cn5 3 cnc5 2 dih5 > ............................................... > h 101 hc107 83 hcn107 79 dih107 > h 102 hc108 84 hcn108 80 dih108 > > cn2 1.384155 > cc3 1.399428 > ccn3 110.943 > nc4 1.373309 > ............................................... > hcn108 109.471 > dih108 60.000 > > 36 37 F > 37 56 F > 7 36 37 38 F > 38 37 56 57 F > 7 36 F > 37 38 F > 56 57 F > 6 7 36 F > 37 38 39 F > 56 57 58 F > 2 6 7 36 F > 37 38 39 40 F > 56 57 58 59 F > > Probably I have to mention that I use dummy atoms to set my constrains. F= or example I fix the distance between 2 dummy atoms but I see that during t= he geometry optimization these distance increases. > > I will appreciate any help, > Roman > > > > -=3D This is automatically added to each message by the mailing script = =3D-> > > --=20 ------------------------------------------------------ Xun-Lei Ding Associate Research Professor of Physical Chemistry State Key Lab for Struct. Chem. of Unstable and Stable Species Institute of Chemistry, The Chinese Academy of Sciences Zhongguancun North First Street 2=A3=AC Beijing 100190, P. R. China Phone 86-10-62568330 Fax 86-10-62559373 From owner-chemistry@ccl.net Thu Apr 2 23:40:01 2009 From: "Dave Winkler dave.winkler _ csiro.au" To: CCL Subject: CCL: Please post on CCL-net Message-Id: <-39001-090402225234-14527-mvqMLjMh3OyXTz5eojmBRg{}server.ccl.net> X-Original-From: Dave Winkler Content-Type: multipart/alternative; boundary="============_-973397478==_ma============" Date: Fri, 3 Apr 2009 13:16:56 +1100 MIME-Version: 1.0 Sent to CCL by: Dave Winkler [dave.winkler===csiro.au] --============_-973397478==_ma============ Content-Type: text/plain; charset="us-ascii"; format=flowed International Medicinal Chemistry Congress AIMECS09 http://www.aimecs09.org Cairns, August 23-27 2009 Gateway to the world heritage-listed Great Barrier Reef and Daintree Rainforest. Registration and abstract submission now open. The program is almost complete, and we have been fortunate to have the ACS, Royal Australian Chemical Institute, and European Federation for Medicinal Chemistry co-organize the program. We will have a diverse range of high quality presentations addressing the conference theme of "Pushing the Boundaries of Medicinal Chemistry". The sessions topics cover: gastrointestinal and metabolic health; peptide self-assembly and peptidomimetics; new techniques and paradigms in medicinal chemistry; tropical medicine and climate change; ion channels and class II GPCRs; RNAi, the coagulation cascade, epigenetics. Confirmed speakers include:- Peter Seeberger, Max-Planck-Institute for Colloids and Interfaces, Free University Berlin Jeremy Nicholson, Imperial College Andrew Holmes, Bio21 and University of Melbourne Marc Leburthe, INSERM, University of Paris John Rossi, City of Hope Hospital Lei Jiang, Novartis, China Bruce Car, Bristol-Meyers Squibb Sam Chackalamannil, Schering Plough Patrick Lam, Bristol-Meyers Squibb John Flygare, Stanford University and Genentech Yoshikazu Nakamura, Institute of Medical Science, University of Tokyo Shelli McAlpine, San Diego State University Patrick Woster, Wayne State University Take advantage of the low Australian dollar and great air fares to Australia . I hope you will have the opportunity to stay a few extra days and explore the Great Barrier Reef and the Daintree Rainforest, which are very close to Cairns. -- Cheers, Dave Prof. David A. Winkler Email: dave.winkler{}csiro.au President Voice: 61-3-9545-2477 Asian Federation for Medicinal Chemistry Fax: 61-3-9545-2446 c/o CSIRO Molecular and Health Technologies Private Bag 10,Clayton South MDC 3169 Australia Join us at the 7th International Medicinal Chemistry Symposium (AIMECS09) Aug 23-27, 2009, Cairns/Great Barrier Reef, Queensland, Australia http://www.aimecs09.org/ --============_-973397478==_ma============ Content-Type: text/html; charset="us-ascii" Please post on CCL-net
International Medicinal Chemistry Congress

AIMECS09

http://www.aimecs09.org

Cairns, August 23-27 2009
Gateway to the world heritage-listed Great Barrier Reef and Daintree Rainforest.

Registration and abstract submission now open.

The program is almost complete, and we have been fortunate to have the ACS, Royal Australian Chemical Institute, and European Federation for Medicinal Chemistry co-organize the program. We will have a diverse range of high quality presentations addressing the conference theme of "Pushing the Boundaries of Medicinal Chemistry". The sessions topics cover: gastrointestinal and metabolic health; peptide self-assembly and peptidomimetics; new techniques and paradigms in medicinal chemistry; tropical medicine and climate change; ion channels and class II GPCRs; RNAi, the coagulation cascade, epigenetics.
Confirmed speakers include:-

Peter Seeberger, Max-Planck-Institute for Colloids and Interfaces, Free University Berlin
Jeremy Nicholson, Imperial College
Andrew Holmes, Bio21 and University of Melbourne
Marc Leburthe, INSERM, University of Paris
John Rossi, City of Hope Hospital
Lei Jiang, Novartis, China
Bruce Car, Bristol-Meyers Squibb
Sam Chackalamannil, Schering Plough
Patrick Lam, Bristol-Meyers Squibb
John Flygare, Stanford University and Genentech
Yoshikazu Nakamura, Institute of Medical Science, University of Tokyo
Shelli McAlpine, San Diego State University
Patrick Woster, Wayne State University

Take advantage of the low Australian dollar and great air fares to Australia . I hope you will have the opportunity to stay a few extra days and explore the Great Barrier Reef and the Daintree Rainforest, which are very close to Cairns. 

--
Cheers,

Dave

Prof. David A. Winkler                               Email: dave.winkler{}csiro.au
President                                   Voice: 61-3-9545-2477
Asian Federation for Medicinal Chemistry   Fax:   61-3-9545-2446
c/o CSIRO Molecular and Health Technologies               
Private Bag 10,Clayton South MDC 3169 
Australia
               
Join us at the 7th International Medicinal Chemistry Symposium (AIMECS09) Aug 23-27, 2009, Cairns/Great Barrier Reef, Queensland, Australia  http://www.aimecs09.org/
--============_-973397478==_ma============--